Chloride, an important negatively charged electrolyte,Chloride is present in the extracellular spaces in combination with sodium and hydrogen. Chloride has two main bodily functions :1-Chloride help to control the distribution of water between the cells and blood plasma, Chloride help to maintain the acid-base balance in the body.
Normal Range of Chloride
90-110 mEq/L
90-110 mEq/L
Variations from Normal. Variations in chloride levels must always be considered in relation to other electrolytes, particularly sodium and bicarbonate.
An increase in plasma chloride will correspond to an increase in sodium levels or a decrease in plasma bicarbonate levels. Measuring chlorides can be helpful in diagnosing acid-base and water balance disorders.
Increases in plasma chloride levels are seen in dehydration, eclampsia, Cushing's syndrome, and anemia. Plasma chloride is decreased with severe vomiting, diarrhea, burns, and heat exhaustion. Other diseases and syndromes that result in chloride deficits include ulcerative colitis, Addison's disease, and diabetic acidosis.
An increase in plasma chloride will correspond to an increase in sodium levels or a decrease in plasma bicarbonate levels. Measuring chlorides can be helpful in diagnosing acid-base and water balance disorders.
Increases in plasma chloride levels are seen in dehydration, eclampsia, Cushing's syndrome, and anemia. Plasma chloride is decreased with severe vomiting, diarrhea, burns, and heat exhaustion. Other diseases and syndromes that result in chloride deficits include ulcerative colitis, Addison's disease, and diabetic acidosis.
Interfering Circumstances of Chloride . Drugs that may cause an increase in chloride levels are androgens, cortisone preparations, estrogens, and nonsteroidal anti-inflammatory drugs. Decreased chloride levels can be associated with corticosteroids, hydrocortisone, and diuretics containing thiazide or mercury.
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